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Rescue of Methyl-CpG Binding Protein 2 Dysfunction-induced Defects in Newborn Neurons by Pentobarbital

Rett syndrome is a neurodevelopmental disorder that usually arises from mutations or deletions in methyl-CpG binding protein 2 (MeCP2), a transcriptional regulator that affects neuronal development and maturation without causing cell loss. Here, we show that silencing of MeCP2 decreased neurite arbo...

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Detalles Bibliográficos
Autores principales: Ma, Dongliang, Yoon, Su-In, Yang, Chih-Hao, Marcy, Guillaume, Zhao, Na, Leong, Wan-Ying, Ganapathy, Vinu, Han, Ju, Van Dongen, Antonius M. J., Hsu, Kuei-Sen, Ming, Guo-Li, Augustine, George J., Goh, Eyleen L. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404443/
https://www.ncbi.nlm.nih.gov/pubmed/25753729
http://dx.doi.org/10.1007/s13311-015-0343-0