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Rescue of Methyl-CpG Binding Protein 2 Dysfunction-induced Defects in Newborn Neurons by Pentobarbital
Rett syndrome is a neurodevelopmental disorder that usually arises from mutations or deletions in methyl-CpG binding protein 2 (MeCP2), a transcriptional regulator that affects neuronal development and maturation without causing cell loss. Here, we show that silencing of MeCP2 decreased neurite arbo...
Autores principales: | Ma, Dongliang, Yoon, Su-In, Yang, Chih-Hao, Marcy, Guillaume, Zhao, Na, Leong, Wan-Ying, Ganapathy, Vinu, Han, Ju, Van Dongen, Antonius M. J., Hsu, Kuei-Sen, Ming, Guo-Li, Augustine, George J., Goh, Eyleen L. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404443/ https://www.ncbi.nlm.nih.gov/pubmed/25753729 http://dx.doi.org/10.1007/s13311-015-0343-0 |
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