RAD51, XRCC3, and XRCC2 mutation screening in Finnish breast cancer families

Majority of the known breast cancer susceptibility genes have a role in DNA repair and the most important high-risk genes BRCA1 and BRCA2 are specifically involved in the homologous recombination repair (HRR) of DNA double-strand breaks. A central player in HRR is RAD51 that binds DNA at the damage...

Descripción completa

Detalles Bibliográficos
Autores principales: Pelttari, Liisa M, Kiiski, Johanna I, Ranta, Salla, Vilske, Sara, Blomqvist, Carl, Aittomäki, Kristiina, Nevanlinna, Heli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404470/
https://www.ncbi.nlm.nih.gov/pubmed/25918678
http://dx.doi.org/10.1186/s40064-015-0880-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404470/
https://www.ncbi.nlm.nih.gov/pubmed/25918678
http://dx.doi.org/10.1186/s40064-015-0880-3

Ejemplares similares