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An Endogenous Nanomineral Chaperones Luminal Antigen and Peptidoglycan to Intestinal Immune Cells

In humans and other mammals, it is known that calcium and phosphate ions are secreted from the distal small intestine into the lumen. However, why this secretion occurs is unclear. Here, we show that the process leads to the formation of amorphous magnesium-substituted calcium phosphate nanoparticle...

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Detalles Bibliográficos
Autores principales: Powell, Jonathan J, Thomas-McKay, Emma, Thoree, Vinay, Robertson, Jack, Hewitt, Rachel E, Skepper, Jeremy N, Brown, Andy, Hernandez-Garrido, Juan Carlos, Midgley, Paul A, Gomez-Morilla, Inmaculada, Grime, Geoffrey W, Kirkby, Karen J, Mabbott, Neil A, Donaldson, David S, Williams, Ifor R, Rios, Daniel, Girardin, Stephen E, Haas, Carolin T, Bruggraber, Sylvaine FA, Laman, Jon D, Tanriver, Yakup, Lombardi, Giovanna, Lechler, Robert, Thompson, Richard P H, Pele, Laetitia C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404757/
https://www.ncbi.nlm.nih.gov/pubmed/25751305
http://dx.doi.org/10.1038/nnano.2015.19