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Inducible and combinatorial gene manipulation in mouse brain

We have deployed recombinant adeno-associated viruses equipped with tetracycline-controlled genetic switches to manipulate gene expression in mouse brain. Here, we show a combinatorial genetic approach for inducible, cell type-specific gene expression and Cre/loxP mediated gene recombination in diff...

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Detalles Bibliográficos
Autores principales: Dogbevia, Godwin K., Marticorena-Alvarez, Ricardo, Bausen, Melanie, Sprengel, Rolf, Hasan, Mazahir T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404871/
https://www.ncbi.nlm.nih.gov/pubmed/25954155
http://dx.doi.org/10.3389/fncel.2015.00142