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Engineered bacterial hydrophobic oligopeptide repeats in a synthetic yeast prion, [REP-PSI(+)]

The yeast translation termination factor Sup35p, by aggregating as the [PSI(+)] prion, enables ribosomes to read-through stop codons, thus expanding the diversity of the Saccharomyces cerevisiae proteome. Yeast prions are functional amyloids that replicate by templating their conformation on native...

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Detalles Bibliográficos
Autores principales: Gasset-Rosa, Fátima, Giraldo, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404881/
https://www.ncbi.nlm.nih.gov/pubmed/25954252
http://dx.doi.org/10.3389/fmicb.2015.00311