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Engineered bacterial hydrophobic oligopeptide repeats in a synthetic yeast prion, [REP-PSI(+)]
The yeast translation termination factor Sup35p, by aggregating as the [PSI(+)] prion, enables ribosomes to read-through stop codons, thus expanding the diversity of the Saccharomyces cerevisiae proteome. Yeast prions are functional amyloids that replicate by templating their conformation on native...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404881/ https://www.ncbi.nlm.nih.gov/pubmed/25954252 http://dx.doi.org/10.3389/fmicb.2015.00311 |