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Divergent and convergent evolution in metastases suggest treatment strategies based on specific metastatic sites
Background and objective: Systemic therapy for metastatic cancer is currently determined exclusively by the site of tumor origin. Yet, there is increasing evidence that the molecular characteristics of metastases significantly differ from the primary tumor. We define the evolutionary dynamics of met...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404930/ https://www.ncbi.nlm.nih.gov/pubmed/25794501 http://dx.doi.org/10.1093/emph/eov006 |