Interferon-γ Suppresses Intestinal Epithelial Aquaporin-1 Expression via Janus Kinase and STAT3 Activation

Inflammatory bowel diseases are associated with dysregulated electrolyte and water transport and resultant diarrhea. Aquaporins are transmembrane proteins that function as water channels in intestinal epithelial cells. We investigated the effect of the inflammatory cytokine, interferon-γ, which is a...

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Detalles Bibliográficos
Autores principales: Dicay, Michael S., Hirota, Christina L., Ronaghan, Natalie J., Peplowski, Michael A., Zaheer, Raza S., Carati, Colin A., MacNaughton, Wallace K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405000/
https://www.ncbi.nlm.nih.gov/pubmed/25793528
http://dx.doi.org/10.1371/journal.pone.0118713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405000/
https://www.ncbi.nlm.nih.gov/pubmed/25793528
http://dx.doi.org/10.1371/journal.pone.0118713

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