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Synapsin III Acts Downstream of Semaphorin 3A/CDK5 Signaling to Regulate Radial Migration and Orientation of Pyramidal Neurons In Vivo

Synapsin III (SynIII) is a phosphoprotein that is highly expressed at early stages of neuronal development. Whereas in vitro evidence suggests a role for SynIII in neuronal differentiation, in vivo evidence is lacking. Here, we demonstrate that in vivo downregulation of SynIII expression affects neu...

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Detalles Bibliográficos
Autores principales: Perlini, Laura E., Szczurkowska, Joanna, Ballif, Bryan A., Piccini, Alessandra, Sacchetti, Silvio, Giovedì, Silvia, Benfenati, Fabio, Cancedda, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405008/
https://www.ncbi.nlm.nih.gov/pubmed/25843720
http://dx.doi.org/10.1016/j.celrep.2015.03.022