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Thymus medulla fosters generation of natural Treg cells, invariant γδ T cells, and invariant NKT cells: What we learn from intrathymic migration

The organization of the thymus into distinct cortical and medullary regions enables it to control the step-wise migration and development of immature T-cell precursors. Such a process provides access to specialized cortical and medullary thymic epithelial cells at defined stages of maturation, ensur...

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Detalles Bibliográficos
Autores principales: Cowan, Jennifer E, Jenkinson, William E, Anderson, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405047/
https://www.ncbi.nlm.nih.gov/pubmed/25615828
http://dx.doi.org/10.1002/eji.201445108