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Detection of changes in the locus coeruleus in patients with mild cognitive impairment and Alzheimer's disease: High-resolution fast spin-echo T1-weighted imaging

AIM: Neuronal degeneration in the locus coeruleus occurs in the early phase of Alzheimer's disease, similar to mild cognitive impairment. The locus coeruleus produces norepinephrine, a deficiency of which causes both memory disturbance and psychological symptoms. Thus, we evaluated signal alter...

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Detalles Bibliográficos
Autores principales: Takahashi, Junko, Shibata, Toshihide, Sasaki, Makoto, Kudo, Masako, Yanezawa, Hisashi, Obara, Satoko, Kudo, Kohsuke, Ito, Kenji, Yamashita, Fumio, Terayama, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405055/
https://www.ncbi.nlm.nih.gov/pubmed/24661561
http://dx.doi.org/10.1111/ggi.12280