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Detection of changes in the locus coeruleus in patients with mild cognitive impairment and Alzheimer's disease: High-resolution fast spin-echo T1-weighted imaging

AIM: Neuronal degeneration in the locus coeruleus occurs in the early phase of Alzheimer's disease, similar to mild cognitive impairment. The locus coeruleus produces norepinephrine, a deficiency of which causes both memory disturbance and psychological symptoms. Thus, we evaluated signal alter...

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Detalles Bibliográficos
Autores principales:	Takahashi, Junko, Shibata, Toshihide, Sasaki, Makoto, Kudo, Masako, Yanezawa, Hisashi, Obara, Satoko, Kudo, Kohsuke, Ito, Kenji, Yamashita, Fumio, Terayama, Yasuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2015
Materias:	Original Articles: Epidemiology, Clinical Practice and Health
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405055/ https://www.ncbi.nlm.nih.gov/pubmed/24661561 http://dx.doi.org/10.1111/ggi.12280

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