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T Follicular Helper Cells in Transplantation: The Target to Attenuate Antibody-Mediated Allogeneic Responses?

Antibody-mediated, humoral rejection has been recognized as a common cause of transplant dysfunction and is responsible for 30–50 % of failed allografts. The production of antibody is dependent on instructions from memory CD4+ T helper cells that interact with antigen-specific B cells. Recently, a s...

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Detalles Bibliográficos
Autores principales: Baan, Carla C., de Graav, Gretchen N., Boer, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405228/
https://www.ncbi.nlm.nih.gov/pubmed/25927019
http://dx.doi.org/10.1007/s40472-014-0019-4