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Mechanical Stretch Induces Apoptosis Regulator TRB3 in Cultured Cardiomyocytes and Volume-Overloaded Heart

The expression of TRB3 (tribbles 3), an apoptosis regulated gene, increases during endoplasmic reticulum (ER) stress. How mechanical stress affects the regulation of TRB3 in cardiomyocytes during apoptosis is not fully understood. An in vivo model of aorta-caval shunt in adult rats demonstrated the...

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Detalles Bibliográficos
Autores principales: Cheng, Wen-Pin, Wang, Bao-Wei, Lo, Huey-Ming, Shyu, Kou-Gi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405267/
https://www.ncbi.nlm.nih.gov/pubmed/25898323
http://dx.doi.org/10.1371/journal.pone.0123235