Blockage of Conformational Changes of Heat Shock Protein gp96 on Cell Membrane by a α-Helix Peptide Inhibits HER2 Dimerization and Signaling in Breast Cancer

Cell membrane translocation of heat shock protein gp96 from the endoplasmic reticulum has been observed in multiple tumors and is associated with tumor malignancy. However, the cancer-intrinsic function and the related mechanism of cell membrane gp96 as a pro-oncogenic chaperone remain further eluci...

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Detalles Bibliográficos
Autores principales: Li, Xin, Wang, Baozhong, Liu, Weiwei, Gui, Mingming, Peng, Zheng, Meng, Songdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405268/
https://www.ncbi.nlm.nih.gov/pubmed/25898135
http://dx.doi.org/10.1371/journal.pone.0124647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405268/
https://www.ncbi.nlm.nih.gov/pubmed/25898135
http://dx.doi.org/10.1371/journal.pone.0124647

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