Enhancement of CD8(+) T-cell memory by removal of a vaccinia virus nuclear factor-κB inhibitor

Factors influencing T-cell responses are important for vaccine development but are incompletely understood. Here, vaccinia virus (VACV) protein N1 is shown to impair the development of both effector and memory CD8(+) T cells and this correlates with its inhibition of nuclear factor-κB (NF-κB) activa...

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Detalles Bibliográficos
Autores principales: Ren, Hongwei, Ferguson, Brian J, de Motes, Carlos Maluquer, Sumner, Rebecca P, Harman, Laura E R, Smith, Geoffrey L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405322/
https://www.ncbi.nlm.nih.gov/pubmed/25382035
http://dx.doi.org/10.1111/imm.12422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405322/
https://www.ncbi.nlm.nih.gov/pubmed/25382035
http://dx.doi.org/10.1111/imm.12422

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