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Competition between VanU(G) Repressor and VanR(G) Activator Leads to Rheostatic Control of vanG Vancomycin Resistance Operon Expression
Enterococcus faecalis BM4518 is resistant to vancomycin by synthesis of peptidoglycan precursors ending in D-alanyl-D-serine. In the chromosomal vanG locus, transcription of the resistance genes from the P(YG) resistance promoter is inducible and, upstream from these genes, there is an unusual three...
Autores principales: | Depardieu, Florence, Mejean, Vincent, Courvalin, Patrice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405338/ https://www.ncbi.nlm.nih.gov/pubmed/25898178 http://dx.doi.org/10.1371/journal.pgen.1005170 |
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