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Distinct Spatial Ca(2+) Signatures Selectively Activate Different NFAT Transcription Factor Isoforms

Protein isoforms are widely expressed in biological systems. How isoforms that co-exist within the same sub-cellular domain are differentially activated remains unclear. Here, we compare the regulatory mechanism of two closely related transcription factor isoforms, NFAT1 and NFAT4, that migrate from...

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Detalles Bibliográficos
Autores principales: Kar, Pulak, Parekh, Anant B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405353/
https://www.ncbi.nlm.nih.gov/pubmed/25818645
http://dx.doi.org/10.1016/j.molcel.2015.02.027