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Distinct Spatial Ca(2+) Signatures Selectively Activate Different NFAT Transcription Factor Isoforms
Protein isoforms are widely expressed in biological systems. How isoforms that co-exist within the same sub-cellular domain are differentially activated remains unclear. Here, we compare the regulatory mechanism of two closely related transcription factor isoforms, NFAT1 and NFAT4, that migrate from...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405353/ https://www.ncbi.nlm.nih.gov/pubmed/25818645 http://dx.doi.org/10.1016/j.molcel.2015.02.027 |