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Corticosteroids Augment BRAF Inhibitor Vemurafenib Induced Lymphopenia and Risk of Infection

We have previously demonstrated an impact of the BRAF inhibitor vemurafenib on patient lymphocyte counts. In the current study, the extent to which concomitant use of corticosteroids in BRAF inhibitor treated patients affects lymphocyte counts and predisposes to infection was investigated. A cohort...

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Detalles Bibliográficos
Autores principales: Sondermann, Wiebke, Griewank, Klaus G., Schilling, Bastian, Livingstone, Elisabeth, Leyh, Julia C., Rompoti, Natalia, Cosgarea, Ioana, Schimming, Tobias, Schadendorf, Dirk, Zimmer, Lisa, Hillen, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405567/
https://www.ncbi.nlm.nih.gov/pubmed/25897843
http://dx.doi.org/10.1371/journal.pone.0124590