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Pentadecapeptide BPC 157 Reduces Bleeding and Thrombocytopenia after Amputation in Rats Treated with Heparin, Warfarin, L-NAME and L-Arginine

BACKGROUND: BPC 157 is a stable gastric pentadecapeptide recently implicated with a role in hemostasis. While NO is largely implicated in hemostatic mechanisms, in tail-amputation-models under heparin- and warfarin-administration, both the NO-synthase (NOS)-blocker, L-NAME (prothrombotic) and the NO...

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Detalles Bibliográficos
Autores principales: Stupnisek, Mirjana, Kokot, Antonio, Drmic, Domagoj, Hrelec Patrlj, Masa, Zenko Sever, Anita, Kolenc, Danijela, Radic, Bozo, Suran, Jelena, Bojic, Davor, Vcev, Aleksandar, Seiwerth, Sven, Sikiric, Predrag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405609/
https://www.ncbi.nlm.nih.gov/pubmed/25897838
http://dx.doi.org/10.1371/journal.pone.0123454