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New insights into the FLPergic complements of parasitic nematodes: Informing deorphanisation approaches

FMRFamide-like peptide (FLP) receptors are appealing as putative anthelmintic targets. To date, 31 flp-encoding genes have been identified in Caenorhabditis elegans and thirteen FLP-activated G-protein coupled receptors (FLP-GPCRs) have been reported. The lack of knowledge on FLPs and FLP-GPCRs in p...

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Detalles Bibliográficos
Autores principales: McCoy, Ciaran J., Atkinson, Louise E., Zamanian, Mostafa, McVeigh, Paul, Day, Tim A., Kimber, Michael J., Marks, Nikki J., Maule, Aaron G., Mousley, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. on behalf of the European Proteomics Association (EuPA) 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405611/
https://www.ncbi.nlm.nih.gov/pubmed/26366373
http://dx.doi.org/10.1016/j.euprot.2014.04.002