The non-peptide thrombopoietin receptor agonist eltrombopag stimulates megakaryopoiesis in bone marrow cells from patients with relapsed multiple myeloma

BACKGROUND: Thrombocytopenia is a significant problem in patients with relapsed or refractory multiple myeloma, precipitating a need for supportive platelet transfusions and necessitating decreases in delivered doses of chemotherapy. Eltrombopag is a non-peptide, small molecule thrombopoietin (TPO)...

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Detalles Bibliográficos
Autores principales: Jeong, Jee-Yeong, Levine, Michelle S, Abayasekara, Nirmalee, Berliner, Nancy, Laubach, Jacob, Vanasse, Gary J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405817/
https://www.ncbi.nlm.nih.gov/pubmed/25886818
http://dx.doi.org/10.1186/s13045-015-0136-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405817/
https://www.ncbi.nlm.nih.gov/pubmed/25886818
http://dx.doi.org/10.1186/s13045-015-0136-2

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