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The non-peptide thrombopoietin receptor agonist eltrombopag stimulates megakaryopoiesis in bone marrow cells from patients with relapsed multiple myeloma
BACKGROUND: Thrombocytopenia is a significant problem in patients with relapsed or refractory multiple myeloma, precipitating a need for supportive platelet transfusions and necessitating decreases in delivered doses of chemotherapy. Eltrombopag is a non-peptide, small molecule thrombopoietin (TPO)...
Autores principales: | Jeong, Jee-Yeong, Levine, Michelle S, Abayasekara, Nirmalee, Berliner, Nancy, Laubach, Jacob, Vanasse, Gary J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405817/ https://www.ncbi.nlm.nih.gov/pubmed/25886818 http://dx.doi.org/10.1186/s13045-015-0136-2 |
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