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Ubiquitinated proteins enriched from tumor cells by a ubiquitin binding protein Vx3(A7) as a potent cancer vaccine

BACKGROUND: Our previous studies have demonstrated that autophagosome-enriched vaccine (named DRibbles: DRiPs-containing blebs) induce a potent anti-tumor efficacy in different murine tumor models, in which DRibble-containing ubiquitinated proteins are efficient tumor-specific antigen source for the...

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Detalles Bibliográficos
Autores principales: Aldarouish, Mohanad, Wang, Huzhan, Zhou, Meng, Hu, Hong-Ming, Wang, Li-xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405905/
https://www.ncbi.nlm.nih.gov/pubmed/25886865
http://dx.doi.org/10.1186/s13046-015-0156-3