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Integrative analyses identify modulators of response to neoadjuvant aromatase inhibitors in patients with early breast cancer

INTRODUCTION: Aromatase inhibitors (AIs) are a vital component of estrogen receptor positive (ER+) breast cancer treatment. De novo and acquired resistance, however, is common. The aims of this study were to relate patterns of copy number aberrations to molecular and proliferative response to AIs, t...

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Detalles Bibliográficos
Autores principales: López-Knowles, Elena, Wilkerson, Paul M, Ribas, Ricardo, Anderson, Helen, Mackay, Alan, Ghazoui, Zara, Rani, Aradhana, Osin, Peter, Nerurkar, Ash, Renshaw, Lorna, Larionov, Alexey, Miller, William R, Dixon, J Michael, Reis-Filho, Jorge S, Dunbier, Anita K, Martin, Lesley-Ann, Dowsett, Mitch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406016/
https://www.ncbi.nlm.nih.gov/pubmed/25888249
http://dx.doi.org/10.1186/s13058-015-0532-0