Neuroprotective effects of DAHP and Triptolide in focal cerebral ischemia via apoptosis inhibition and PI3K/Akt/mTOR pathway activation

Triptolide (TP), one of the major active components of the traditional Chinese herb Tripterygium wilfordii Hook F, and 2, 4-diamino-6-hydroxypyrimidine (DAHP), an inhibitor of tetrahydrobiopterin (BH4) synthesis, have been reported to have potent anti-inflammatory and immunosuppressive properties. H...

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Detalles Bibliográficos
Autores principales: Li, Weiyun, Yang, Yang, Hu, Zhiying, Ling, Shucai, Fang, Marong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroanatomy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406066/
https://www.ncbi.nlm.nih.gov/pubmed/25954164
http://dx.doi.org/10.3389/fnana.2015.00048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406066/
https://www.ncbi.nlm.nih.gov/pubmed/25954164
http://dx.doi.org/10.3389/fnana.2015.00048

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