Activated platelets release sphingosine 1-phosphate and induce hypersensitivity to noxious heat stimuli in vivo

At the site of injury activated platelets release various mediators, one of which is sphingosine 1-phosphate (S1P). It was the aim of this study to explore whether activated human platelets had a pronociceptive effect in an in vivo mouse model and whether this effect was based on the release of S1P...

Descripción completa

Detalles Bibliográficos
Autores principales: Weth, Daniela, Benetti, Camilla, Rauch, Caroline, Gstraunthaler, Gerhard, Schmidt, Helmut, Geisslinger, Gerd, Sabbadini, Roger, Proia, Richard L., Kress, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406086/
https://www.ncbi.nlm.nih.gov/pubmed/25954148
http://dx.doi.org/10.3389/fnins.2015.00140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406086/
https://www.ncbi.nlm.nih.gov/pubmed/25954148
http://dx.doi.org/10.3389/fnins.2015.00140

Ejemplares similares