Endocytic deficiency induced by ITSN-1s knockdown alters the Smad2/3-Erk1/2 signaling balance downstream of Alk5

Recently, we demonstrated in cultured endothelial cells and in vivo that deficiency of an isoform of intersectin-1, ITSN-1s, impairs caveolae and clathrin-mediated endocytosis and functionally upregulates compensatory pathways and their morphological carriers (i.e. enlarged endocytic structures, mem...

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Detalles Bibliográficos
Autores principales: Bardita, Cristina, Predescu, Dan N., Sha, Fei, Patel, Monal, Balaji, Ganesh, Predescu, Sanda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406123/
https://www.ncbi.nlm.nih.gov/pubmed/25720380
http://dx.doi.org/10.1242/jcs.163030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406123/
https://www.ncbi.nlm.nih.gov/pubmed/25720380
http://dx.doi.org/10.1242/jcs.163030

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