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Endocytic deficiency induced by ITSN-1s knockdown alters the Smad2/3-Erk1/2 signaling balance downstream of Alk5
Recently, we demonstrated in cultured endothelial cells and in vivo that deficiency of an isoform of intersectin-1, ITSN-1s, impairs caveolae and clathrin-mediated endocytosis and functionally upregulates compensatory pathways and their morphological carriers (i.e. enlarged endocytic structures, mem...
Autores principales: | Bardita, Cristina, Predescu, Dan N., Sha, Fei, Patel, Monal, Balaji, Ganesh, Predescu, Sanda A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406123/ https://www.ncbi.nlm.nih.gov/pubmed/25720380 http://dx.doi.org/10.1242/jcs.163030 |
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