Follow-up: Prospective compound design using the ‘SAR Matrix’ method and matrix-derived conditional probabilities of activity

In a previous Method Article, we have presented the ‘Structure-Activity Relationship (SAR) Matrix’ (SARM) approach. The SARM methodology is designed to systematically extract structurally related compound series from screening or chemical optimization data and organize these series and associated SA...

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Detalles Bibliográficos
Autores principales: Gupta-Ostermann, Disha, Hirose, Yoichiro, Odagami, Takenao, Kouji, Hiroyuki, Bajorath, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2015
Materias:
Method Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406192/
https://www.ncbi.nlm.nih.gov/pubmed/25949808
http://dx.doi.org/10.12688/f1000research.6271.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406192/
https://www.ncbi.nlm.nih.gov/pubmed/25949808
http://dx.doi.org/10.12688/f1000research.6271.2

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