XIAP and cIAP1 amplifications induce Beclin 1-dependent autophagy through NFκB activation

Perturbations in autophagy and apoptosis are associated with cancer development. XIAP and cIAP1 are two members of the inhibitors of apoptosis protein family whose expression is elevated in different cancers. Here we report that XIAP and cIAP1 induce autophagy by upregulating the transcription of Be...

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Detalles Bibliográficos
Autores principales: Lin, Fang, Ghislat, Ghita, Luo, Shouqing, Renna, Maurizio, Siddiqi, Farah, Rubinsztein, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406300/
https://www.ncbi.nlm.nih.gov/pubmed/25669656
http://dx.doi.org/10.1093/hmg/ddv052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406300/
https://www.ncbi.nlm.nih.gov/pubmed/25669656
http://dx.doi.org/10.1093/hmg/ddv052

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