Proteochemometric Modeling of the Antigen-Antibody Interaction: New Fingerprints for Antigen, Antibody and Epitope-Paratope Interaction

Despite the high specificity between antigen and antibody binding, similar epitopes can be recognized or cross-neutralized by paratopes of antibody with different binding affinities. How to accurately characterize this slight variation which may or may not change the antigen-antibody binding affinit...

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Detalles Bibliográficos
Autores principales: Qiu, Tianyi, Xiao, Han, Zhang, Qingchen, Qiu, Jingxuan, Yang, Yiyan, Wu, Dingfeng, Cao, Zhiwei, Zhu, Ruixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406442/
https://www.ncbi.nlm.nih.gov/pubmed/25901362
http://dx.doi.org/10.1371/journal.pone.0122416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406442/
https://www.ncbi.nlm.nih.gov/pubmed/25901362
http://dx.doi.org/10.1371/journal.pone.0122416

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