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Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance

Successful control of falciparum malaria depends greatly on treatment with artemisinin combination therapies. Thus, reports that resistance to artemisinins (ARTs) has emerged, and that the prevalence of this resistance is increasing, are alarming. ART resistance has recently been linked to mutations...

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Detalles Bibliográficos
Autores principales: Dogovski, Con, Xie, Stanley C., Burgio, Gaetan, Bridgford, Jess, Mok, Sachel, McCaw, James M., Chotivanich, Kesinee, Kenny, Shannon, Gnädig, Nina, Straimer, Judith, Bozdech, Zbynek, Fidock, David A., Simpson, Julie A., Dondorp, Arjen M., Foote, Simon, Klonis, Nectarios, Tilley, Leann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406523/
https://www.ncbi.nlm.nih.gov/pubmed/25901609
http://dx.doi.org/10.1371/journal.pbio.1002132