Evidence that mutation accumulation does not cause aging in Saccharomyces cerevisiae

The concept that mutations cause aging phenotypes could not be directly tested previously due to inability to identify age-related mutations in somatic cells and determine their impact on organismal aging. Here, we subjected Saccharomyces cerevisiae to multiple rounds of replicative aging and assess...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaya, Alaattin, Lobanov, Alexei V, Gladyshev, Vadim N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406665/
https://www.ncbi.nlm.nih.gov/pubmed/25702753
http://dx.doi.org/10.1111/acel.12290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406665/
https://www.ncbi.nlm.nih.gov/pubmed/25702753
http://dx.doi.org/10.1111/acel.12290

Ejemplares similares