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Evidence that mutation accumulation does not cause aging in Saccharomyces cerevisiae

The concept that mutations cause aging phenotypes could not be directly tested previously due to inability to identify age-related mutations in somatic cells and determine their impact on organismal aging. Here, we subjected Saccharomyces cerevisiae to multiple rounds of replicative aging and assess...

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Detalles Bibliográficos
Autores principales:	Kaya, Alaattin, Lobanov, Alexei V, Gladyshev, Vadim N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406665/ https://www.ncbi.nlm.nih.gov/pubmed/25702753 http://dx.doi.org/10.1111/acel.12290

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