The exonuclease Nibbler regulates age-associated traits and modulates piRNA length in Drosophila

Nibbler (Nbr) is a 3′-to-5′ exonuclease that trims the 3′end of microRNAs (miRNAs) to generate different length patterns of miRNAs in Drosophila. Despite its effect on miRNAs, we lack knowledge of its biological significance and whether Nbr affects other classes of small RNAs such as piRNAs and endo...

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Detalles Bibliográficos
Autores principales: Feltzin, Virzhiniya L, Khaladkar, Mugdha, Abe, Masashi, Parisi, Michael, Hendriks, Gert-Jan, Kim, Junhyong, Bonini, Nancy M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406673/
https://www.ncbi.nlm.nih.gov/pubmed/25754031
http://dx.doi.org/10.1111/acel.12323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406673/
https://www.ncbi.nlm.nih.gov/pubmed/25754031
http://dx.doi.org/10.1111/acel.12323

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