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The exonuclease Nibbler regulates age-associated traits and modulates piRNA length in Drosophila
Nibbler (Nbr) is a 3′-to-5′ exonuclease that trims the 3′end of microRNAs (miRNAs) to generate different length patterns of miRNAs in Drosophila. Despite its effect on miRNAs, we lack knowledge of its biological significance and whether Nbr affects other classes of small RNAs such as piRNAs and endo...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BlackWell Publishing Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406673/ https://www.ncbi.nlm.nih.gov/pubmed/25754031 http://dx.doi.org/10.1111/acel.12323 |