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Regulation of the p19(Arf)/p53 pathway by histone acetylation underlies neural stem cell behavior in senescence-prone SAMP8 mice
Brain aging is associated with increased neurodegeneration and reduced neurogenesis. B1/neural stem cells (B1-NSCs) of the mouse subependymal zone (SEZ) support the ongoing production of olfactory bulb interneurons, but their neurogenic potential is progressively reduced as mice age. Although age-re...
Autores principales: | Soriano-Cantón, Raúl, Perez-Villalba, Ana, Morante-Redolat, José Manuel, Marqués-Torrejón, María Ángeles, Pallás, Mercé, Pérez-Sánchez, Francisco, Fariñas, Isabel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406674/ https://www.ncbi.nlm.nih.gov/pubmed/25728253 http://dx.doi.org/10.1111/acel.12328 |
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