Cargando…

Accelerated epigenetic aging in Down syndrome

Down Syndrome (DS) entails an increased risk of many chronic diseases that are typically associated with older age. The clinical manifestations of accelerated aging suggest that trisomy 21 increases the biological age of tissues, but molecular evidence for this hypothesis has been sparse. Here, we u...

Descripción completa

Detalles Bibliográficos
Autores principales: Horvath, Steve, Garagnani, Paolo, Bacalini, Maria Giulia, Pirazzini, Chiara, Salvioli, Stefano, Gentilini, Davide, Di Blasio, Anna Maria, Giuliani, Cristina, Tung, Spencer, Vinters, Harry V, Franceschi, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406678/
https://www.ncbi.nlm.nih.gov/pubmed/25678027
http://dx.doi.org/10.1111/acel.12325