Oncogenic NRAS Primes Primary Acute Myeloid Leukemia Cells for Differentiation

RAS mutations are frequently found among acute myeloid leukemia patients (AML), generating a constitutively active signaling protein changing cellular proliferation, differentiation and apoptosis. We have previously shown that treatment of AML patients with high-dose cytarabine is preferentially ben...

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Detalles Bibliográficos
Autores principales: Brendel, Cornelia, Teichler, Sabine, Millahn, Axel, Stiewe, Thorsten, Krause, Michael, Stabla, Kathleen, Ross, Petra, Huynh, Minh, Illmer, Thomas, Mernberger, Marco, Barckhausen, Christina, Neubauer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406710/
https://www.ncbi.nlm.nih.gov/pubmed/25901794
http://dx.doi.org/10.1371/journal.pone.0123181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406710/
https://www.ncbi.nlm.nih.gov/pubmed/25901794
http://dx.doi.org/10.1371/journal.pone.0123181

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