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Oncogenic NRAS Primes Primary Acute Myeloid Leukemia Cells for Differentiation

RAS mutations are frequently found among acute myeloid leukemia patients (AML), generating a constitutively active signaling protein changing cellular proliferation, differentiation and apoptosis. We have previously shown that treatment of AML patients with high-dose cytarabine is preferentially ben...

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Detalles Bibliográficos
Autores principales:	Brendel, Cornelia, Teichler, Sabine, Millahn, Axel, Stiewe, Thorsten, Krause, Michael, Stabla, Kathleen, Ross, Petra, Huynh, Minh, Illmer, Thomas, Mernberger, Marco, Barckhausen, Christina, Neubauer, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406710/ https://www.ncbi.nlm.nih.gov/pubmed/25901794 http://dx.doi.org/10.1371/journal.pone.0123181

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