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Re-replication of a Centromere Induces Chromosomal Instability and Aneuploidy

The faithful inheritance of chromosomes during cell division requires their precise replication and segregation. Numerous mechanisms ensure that each of these fundamental cell cycle events is performed with a high degree of fidelity. The fidelity of chromosomal replication is maintained in part by r...

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Detalles Bibliográficos
Autores principales: Hanlon, Stacey L., Li, Joachim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406714/
https://www.ncbi.nlm.nih.gov/pubmed/25901968
http://dx.doi.org/10.1371/journal.pgen.1005039