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Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma

To gain molecular insights of HBV integration that may contribute to HCC tumorigenesis, we performed whole transcriptome sequencing and whole genome copy number profiling of hepatocellular carcinoma (HCC) samples from 50 Chinese patients. We identified a total of 33 HBV-human integration sites in 16...

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Detalles Bibliográficos
Autores principales: Dong, Hua, Zhang, Lan, Qian, Ziliang, Zhu, Xuehua, Zhu, Guanshan, Chen, Yunqin, Xie, Xiaoying, Ye, Qinghai, Zang, Jie, Ren, Zhenggang, Ji, Qunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406717/
https://www.ncbi.nlm.nih.gov/pubmed/25901726
http://dx.doi.org/10.1371/journal.pone.0123175