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Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma
To gain molecular insights of HBV integration that may contribute to HCC tumorigenesis, we performed whole transcriptome sequencing and whole genome copy number profiling of hepatocellular carcinoma (HCC) samples from 50 Chinese patients. We identified a total of 33 HBV-human integration sites in 16...
Autores principales: | Dong, Hua, Zhang, Lan, Qian, Ziliang, Zhu, Xuehua, Zhu, Guanshan, Chen, Yunqin, Xie, Xiaoying, Ye, Qinghai, Zang, Jie, Ren, Zhenggang, Ji, Qunsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406717/ https://www.ncbi.nlm.nih.gov/pubmed/25901726 http://dx.doi.org/10.1371/journal.pone.0123175 |
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