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Circulating Mitochondrial DAMPs Are Not Effective Inducers of Proteinuria and Kidney Injury in Rodents

Mitochondria in eukaryotic cells are derived from bacteria in evolution. Like bacteria, mitochondria contain DNA with unmethylated CpG motifs and formyl peptides, both of which have recently been shown to be damage associated molecular patterns (DAMPs) and induce immune response and cell injury. Bas...

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Detalles Bibliográficos
Autores principales: He, Jing, Lu, Yuqiu, Xia, Hong, Liang, Yaojun, Wang, Xiao, Bao, Wenduona, Yun, Shifeng, Ye, Yuting, Zheng, Chunxia, Liu, Zhihong, Shi, Shaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406729/
https://www.ncbi.nlm.nih.gov/pubmed/25902071
http://dx.doi.org/10.1371/journal.pone.0124469