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Integrative Omics Analysis of Rheumatoid Arthritis Identifies Non-Obvious Therapeutic Targets

Identifying novel therapeutic targets for the treatment of disease is challenging. To this end, we developed a genome-wide approach of candidate gene prioritization. We independently collocated sets of genes that were implicated in rheumatoid arthritis (RA) pathogenicity through three genome-wide as...

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Detalles Bibliográficos
Autores principales: Whitaker, John W., Boyle, David L., Bartok, Beatrix, Ball, Scott T., Gay, Steffen, Wang, Wei, Firestein, Gary S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406750/
https://www.ncbi.nlm.nih.gov/pubmed/25901943
http://dx.doi.org/10.1371/journal.pone.0124254