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Phosphoethanolamine Transferase LptA in Haemophilus ducreyi Modifies Lipid A and Contributes to Human Defensin Resistance In Vitro

Haemophilus ducreyi resists the cytotoxic effects of human antimicrobial peptides (APs), including α-defensins, β-defensins, and the cathelicidin LL-37. Resistance to LL-37, mediated by the sensitive to antimicrobial peptide (Sap) transporter, is required for H. ducreyi virulence in humans. Cationic...

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Detalles Bibliográficos
Autores principales: Trombley, Michael P., Post, Deborah M. B., Rinker, Sherri D., Reinders, Lorri M., Fortney, Kate R., Zwickl, Beth W., Janowicz, Diane M., Baye, Fitsum M., Katz, Barry P., Spinola, Stanley M., Bauer, Margaret E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406763/
https://www.ncbi.nlm.nih.gov/pubmed/25902140
http://dx.doi.org/10.1371/journal.pone.0124373