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Phosphoethanolamine Transferase LptA in Haemophilus ducreyi Modifies Lipid A and Contributes to Human Defensin Resistance In Vitro
Haemophilus ducreyi resists the cytotoxic effects of human antimicrobial peptides (APs), including α-defensins, β-defensins, and the cathelicidin LL-37. Resistance to LL-37, mediated by the sensitive to antimicrobial peptide (Sap) transporter, is required for H. ducreyi virulence in humans. Cationic...
Autores principales: | Trombley, Michael P., Post, Deborah M. B., Rinker, Sherri D., Reinders, Lorri M., Fortney, Kate R., Zwickl, Beth W., Janowicz, Diane M., Baye, Fitsum M., Katz, Barry P., Spinola, Stanley M., Bauer, Margaret E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406763/ https://www.ncbi.nlm.nih.gov/pubmed/25902140 http://dx.doi.org/10.1371/journal.pone.0124373 |
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