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Novel Bayes Factors That Capture Expert Uncertainty in Prior Density Specification in Genetic Association Studies

Bayes factors (BFs) are becoming increasingly important tools in genetic association studies, partly because they provide a natural framework for including prior information. The Wakefield BF (WBF) approximation is easy to calculate and assumes a normal prior on the log odds ratio (logOR) with a mea...

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Detalles Bibliográficos
Autores principales: Spencer, Amy V., Cox, Angela, Lin, Wei‐Yu, Easton, Douglas F., Michailidou, Kyriaki, Walters, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406822/
https://www.ncbi.nlm.nih.gov/pubmed/25727067
http://dx.doi.org/10.1002/gepi.21891